CLONING AND CHARACTERIZATION OF T-BOX AND FORKHEAD TRANSCRIPTION FACTORS FROM PORIFERA

Authors

  • WERNER E.G. MÜLLER

Abstract

During evolution, the appearance of the mesoderm in Bilateria, with the exception of the Ctenophora, parallels with the appearance of the two perpendicular body axes. The effectors of bilaterian regional specification and pattern formation comprise an evolutionary conserved set of transcription factors related to the superclasses of homeoproteins, forkhead, T-box, Wnt-pathway and zinc-finger proteins. In sponges, the existence of those major regulatory genes causing the establishment of a polar patterning in bilaterians remains to be elucidated. Here we report the isolation and phylogenetic characterization of two T-box genes and four forkhead genes from the demosponge Suberites domuncula (Olivi, 1792).

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Published

2018-05-22